Cardiologia Intervencionista by Eric J Topol, , available at Book Depository with free delivery worldwide. Cardiología. Front Cover. Steven P. Marso, Brian P. Griffin, Eric J. Topol. Marbán, – pages Bibliographic information. QR code for Cardiología. Page 28 – The Clopidogrel in Unstable Angina to Prevent Recurrent Events Trial Investigators. Effects of Clopidogrel in Addition to Aspirin in Patients with Acute.

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Dr Barbanti is the youngest recipient of the prestigious “Thomas J. Linnemeier Spirit of Interventional Cardiology Young Investigator Award” from the Cardiovascular Research Foundation, which has been delivered to him in for his distinguished clinical and cardiologis achievements.

Each participating research team reviewed the economic and regulatory incentives provided by their country’s health system, topol cardiologia major changes in those incentives over the s and s, according to a commonly used framework.


Each team also reviewed how care for heart attacks has changed in their country over the past decade. Different classifications have been proposed and used to define these lesions. For our classification cardiologix use the 3 components of a bifurcation: Respecting that sequence, we propose a new simple intuitive classification which does not demand memorisation. It consists in giving topol cardiologia binary value 1, 0 according to whether each of the segments previously defined is compromised or not.

Abstract Although technical advances enable normal epicardial coronary artery blood topol cardiologia to be restored in most patients suffering myocardial infarction, restoration of blood flow is not always followed by improved myocardial perfusion.


Recently, therefore, interest in the assessment of myocardial perfusion has grown, and a number of different assessment methods are available. The aim of this article was to topol cardiologia an evaluation of the additional information that can be obtained from the widely used cardiologiz of conventional coronary angiography.

We present a review of the data on epicardial coronary artery blood flow both semiquantitative and quantitative and on microvascular blood flow that can be obtained using coronary angiography and discuss their prognostic significance. The theory of the “open artery” is based on two fundamental factors: Whatever the reperfusion method used, as demonstrated in many studies, the final aim is that the angiographic parameter, epicardial blood flow, is normal.

There are several methods to assess the state of coronary microcirculation and myocardial perfusion, from the simplest–analyzing a previously resolved ST-segment elevation in the electrocardiogram ECGto the more complex–positron emission tomography PET.

Many studies topol cardiologia demonstrated the correlation between this parameter and later events such as: With the development of repatency therapy using PCI, the use of these predictors has continued to prove their validity,41 although some studies point out that the difference in mortality between TIMI 2 and 3 grades might not be so marked nowadays with the use of invasive therapies that combine fibrinolytic drugs and PCI.

Nevertheless, this grading system has caddiologia limitations: Topol cardiologia most relevant limitation is its subjectivity, which leads to important discrepancies,61 even when the analyzes assessment is performed by core laboratories cardioolgia wide experience.

The filling time of the left anterior descending coronary artery LAD is higher than in other arteries, because this is normally the longest artery. Given that the filling of this artery can be simultaneously compared with the filling of the circumflex artery, the tendency to assign a TIMI grade 2 flow is much greater than with the right coronary artery RCA.


Finally, we cannot discard the presence of factors that could significantly modify grading, such as the pressure and phase within the cardiac cycle at which the contrast injection is administered, the heart otpol and blood pressure of the patient, the use of vasodilators, etc.

Tratado de Medicina Cardiovascular : Eric J. Topol :

The impact of these factors is discussed in the next section. Corrected TIMI Frame Count In the light of the topol cardiologia limitations of the TIMI flow grading system, new evaluation systems have been developed that more deeply topol cardiologia flow and improve the reproducibility of results: Basically, it quantifies the TIMI flow grade by measuring the time it takes the contrast agent to fill the entire length of the epicardial artery.

In order to standardize the criteria, several distal bifurcations were defined to serve as “final landmarks”: Calculating TIMI frame counts.

The last frame final frame is the image where the contrast begins to fill the final landmark. Distal bifurcations of the 3 epicardial arteries are shown. CD indicates right coronary artery; Cx, cardiklogia topol cardiologia DA, left anterior descending coronary artery. Entertainment Environment Science Simulation Education.